Blood Volume Imaging Technique

For some years now, bolus injections of chelated contrast agents, in particular gadolinium diethylenetriamine pentaacetic acid, have been used to assess regional cerebral blood volume, and, when the mean transit time of the contrast agent through the brain is known, cerebral blood flow. The high paramagnetic nature of these contrast agents alters the relaxation processes of water molecules in their surrounding. Changes are evident as a shortening in the relaxation times, and it is this shortening that is used to obtain a qualitative map of regional cerebral blood volume. The major disadvantages of this technique are the necessity of repeated bolus injections of a contrast agent, the potential for subject motion between injections to mask any regional cerebral blood flow (rCBF) changes, and the limited number of neurological states that can be studied in a single session.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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