Contents

Foreword xv

Preface xix

Contributors xxi

Part I FOUNDATIONAL CONCEPTS 1

1 BIOLOGICAL PSYCHIATRY SKETCHED—PAST, PRESENT, 3 AND FUTURE

Jaak Panksepp

Overture 3

Historical Overview 5

Three Giants of the First Half of the 20th Century 7

Three Great Phases of 20th-century American Psychiatry 9

About 1910-1940: The Meyerian Synthesis of a Holistic Psychobiology 9

World War II through the 1970s: The Psychoanalytic Era 10

Ultrapositivistic Psychopharmacology Era (1970-Present) 12

Dilemma of Psychiatric Diagnostics: DSMs and Beyond 17

Functions of Diagnostics 19

From Pathophysiology to Pathogenesis 20

Perennial Problem: Distinguishing Affective and Cognitive Processes 24

Coda: Intersection of 20th-century Forces Leading to a 21st-century 28 Synthesis

References 29

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