Historical Perspectives

Prior to the advent of modern biological psychiatry, there were no agents that selectively diminished feelings of anxiety. Until the development of the benzodiazepine (BZ) class of minor tranquilizers, the main drugs that could successfully control human anxiety were opioids, alcohol, barbiturates, and meprobamate (Gray, 1987). All of these had serious problems that precluded continuous long-term use, including most prominently pharmacological tolerance, poor safety margins, addictions, and the potential to be used for suicide. However, during the past few decades our neurobiological appreciation of the sources of anxiety (Goddard et al., 1999), from generalized anxiety disorders (Conner and Davidson, 1998) to social phobias (Stein, 1998), has been impressive. Although vigorous new drug development has proceeded in the area, major new payoffs have been modest, except for the emerging use of antidepressants to treat anxiety (Cheetham and Heal, 2000).

Getting to Know Anxiety

Getting to Know Anxiety

Stop Letting Anxiety Rule Your Life And Take Back The Control You Desire Right Now! You don't have to keep letting your anxiety disorder run your life. You can take back your inner power and change your life for the better starting today! In order to have control of a thing, you first must understand it. And that is what this handy little guide will help you do. Understand this illness for what it is. And, what it isn't.

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