Historical Perspectives

Prior to the advent of modern biological psychiatry, there were no agents that selectively diminished feelings of anxiety. Until the development of the benzodiazepine (BZ) class of minor tranquilizers, the main drugs that could successfully control human anxiety were opioids, alcohol, barbiturates, and meprobamate (Gray, 1987). All of these had serious problems that precluded continuous long-term use, including most prominently pharmacological tolerance, poor safety margins, addictions, and the potential to be used for suicide. However, during the past few decades our neurobiological appreciation of the sources of anxiety (Goddard et al., 1999), from generalized anxiety disorders (Conner and Davidson, 1998) to social phobias (Stein, 1998), has been impressive. Although vigorous new drug development has proceeded in the area, major new payoffs have been modest, except for the emerging use of antidepressants to treat anxiety (Cheetham and Heal, 2000).

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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