Schizophrenia is a debilitating psychiatric disorder that affects about 1 percent of the world's population. In 1990, the World Health Organization ranked schizophrenia as one of the 10 leading causes of disability with an annual direct cost of 19 billion US dollars and an additional annual indirect cost of 46 billion US dollars from lost productivity. Two-thirds of people with schizophrenia will require public assistance from government social security systems within a few years after onset. While patients with schizophrenia occupy one-third of the nation's mental hospital beds, many are homeless, and 10 to 15 percent of them will commit suicide.

Despite more than 50,000 published articles and hundreds of symposia, schizophrenia still remains an elusive disease. In this chapter, we will review our present understanding of the disease and the current technology being used to advance this understanding. We will present evidence that schizophrenia is a heterogeneous disease of developmental origin, with problems that arise early in development and span the entire lifetime of the

Textbook of Biological Psychiatry. Edited by Jaak Panksepp Copyright © 2004 by Wiley-Liss, Inc. ISBN: 0-471-43478-7

affected individual. The pharmacological treatment of schizophrenia will be discussed in the next chapter.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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