Genetic and Congenital Hypotheses

the first edition of this book, there has b-

basis of manic-depressive disorder, particularly • biological tools. This research, including both mo

(Craddock & Jones, 1999; Potash & dePaulo, 2000).

Available nants of who have shown thati

(Table 3.2). Overall, rates of manic-depressive disorder in

. 5 to 10 times over rates foun.. in the i the latter group, the rates are 0.5% to 1.5%; in i interestingly, rates or unipolar depression in about two-fold elevated over those in the j rate of depression in the general population (5% to 20%), this twofold increase is a rate of about 20%. Important for this in turn means that the probability that a manic-depressive proband have a child with unipolar depression is greater than the probability that he or she will have a child with manic-depressive disorder (5% to 15% vs.

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Natural Depression Cures

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