Cerebellar Degeneration

Although a definite association between cerebellar degeneration and nutritional deficiency is not established in alcoholism, thiamine deficiency is suggested by the clinical and pathological resemblance to the cerebellar involvement in Wernicke's disease. Alcoholism is the chief risk factor for the development of this disorder, and males are affected more often than females. The main clinical manifestation is a disorder of gait characterized by instability and a widened base. Patients are unable to walk with one foot

placed in front of the other and occasionally there is frank ataxia of the lower extremities, which is best appreciated on a heel-to-shin test. The gait disorder develops gradually, or occasionally in a stepwise fashion. The upper limbs are only rarely involved.

Because this disorder is associated with alcoholism, many patients have evidence of other complications of nutritional deficiency, particularly a polyneuropathy. In alcoholics, alternate causes of gait ataxia include Wernicke's disease, acquired hepatocerebral degeneration, and the effects of head trauma. Cerebellar syndromes featuring prominent speech or oculomotor deficits should suggest another cause for the ataxia, even in alcoholics.

MRI may demonstrate atrophy of the anterosuperior vermis, which is best seen on a midline sagittal image. With the uncertain pathogenesis, the only known effective preventive measure is the treatment of alcoholism. However, it is likely that avoiding nutritional deficiency would eliminate the risk of alcoholic cerebellar degeneration. The utility of vitamin supplementation after the cerebellar degeneration has occurred is unproven. In most cases, the gait disorder progresses over weeks to months, and then persists indefinitely. A small number of patients show only brief manifestations with spontaneous resolution.

Beat The Battle With The Bottle

Beat The Battle With The Bottle

Alcoholism is something that can't be formed in easy terms. Alcoholism as a whole refers to the circumstance whereby there's an obsession in man to keep ingesting beverages with alcohol content which is injurious to health. The circumstance of alcoholism doesn't let the person addicted have any command over ingestion despite being cognizant of the damaging consequences ensuing from it.

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