The cerebellum is not the origin of postural or locomotor responses because total ablation of the cerebellum does

not abolish these responses. The cerebellum, however, refines the force and timing of locomotor and postural responses. Thus, the execution of these responses in an animal with cerebellar ablation is uncoordinated and dysmetric. [10] The cerebellum receives information about each step cycle through the spinocerebellar pathways (see Cha.p.terJ.7) . Many Purkinje cells fire in synchrony with various parts of the step cycle. The cerebellum partially exerts its influence on locomotion by affecting the activity of the reticulospinal, vestibulospinal, and rubrospinal pathways, which are phasically active during stepping and contribute to coordinated rhythmic stepping. Rhythmical firing in these descending bulbospinal pathways is largely abolished by cerebellar ablation. [3] The cerebellar projections to the thalamus and thence to the frontal cortex may also affect gait and balance, although this possibility has not been explored.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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