Memory Related Chemical Changes

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The specific roles of different neurotransmitters in memory are just beginning to be appreciated. The cholinergic system appears to be critical for the acquisition of long-term declarative memories. In healthy subjects, cholinergic antagonists such as scopolamine impair declarative memory performance, whereas agonists such as physostigmine facilitate such performance. y Some nondeclarative forms of memory, however, are not affected by scopolamine. Cholinergic function decreases somewhat with age and greatly in patients with Alzheimer's disease, y and these changes may contribute importantly to corresponding reductions in declarative memory ability.

The catecholamines appear to have an important role in working memory. Dopaminergic function is decreased in patients with Parkinson's disease, who have reduced working memory capacity. There is some evidence that dopamine agonists can improve working memory capacity in patients with Parkinson's disease y and in healthy subjects.y


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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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