Natural Insomnia Program

Cure Insomnia Naturally

Get Instant Access

1. Gajdusek DC, Gibbs CJJ, Alpers M: Experimental transmission of a kuru-like syndrome in chimpanzees. Nature 1966;209:794-796

2. Gibbs CJ Jr, Gajdusek DC, Asher DM, et al: Creutzfeldt-Jakob disease (spongiform encephalopathy): Transmission to the chimpanzee. Science 1968;161:388-389

3. Masters C, Gajdusek D, Gibbs C Jr: Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Straussler syndrome. Brain 1981; 104:559-588

4. Tateishi J, Brown P, Kitamoto T, et al: First experimental transmission of fatal familial insomnia. Nature 1995;376:434-435

5. Alper T, Cramp WA, Haig DA, Clarke MC: Does the agent of scrapie replicate without nucleic acid? Nature 1967;214:764-766

6. Prusiner SB, Gabizon R, McKinley MP: On the biology of prions. Acta Neuropathol (Berl) 1987;72:299-314.

7. Hsiao K, Prusiner SB: Inherited human prion diseases. Neurology 1990;40:1820-1827

8. Priola SA, Caughey B, Wehrly K, Chesebro B: A 60-kDa prion protein (PrP) with properties of both the normal and scrapie-associated forms of PrP. j Biol Chem 1995;70:3299-3305

9. Gajdusek DC: Fantasy of a "virus" from the inorganic world: Pathogenesis of cerebral amyloidoses by polymer nucleating agents and/or "viruses." in Neth r, Gallo rc, Greaves mf, et al (eds): Modern Trends in Human Leukemia VIII. New York, Springer-Verlag, 1989, pp 481-49 .

10. Will RG, Ironside JW, Zeidler M, et al: A new variant of Creutzfeldt- Jakob disease in the UK. Lancet 1996;347:921-925

11. Brown P, Gibbs C Jr, Rodgers-Johnson P, et al: Human spongiform encephalopathy: The National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann Neurol


12. Brown P: Can Creutzfeldt-Jakob disease be transmitted by transfusion? Curr Opinion Hematol 1995;2:472-477.

13. Harrington MG, Merril CR, Asher DM, Gajdusek DC: Abnormal proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. n Engl j Med 1986;315:279-283

14. Hsich G, Kenney K, Gibbs CJ Jr, et al: 14-3-3 protein: A diagnostic cerebrospinal fluid marker for transmissible spongiform encephalopathies. n Engl j Med 1996;335:924-930

15. White CL, Rosenberg RN, Brown P, et al: Precautions in handling tissues, fluids, and other contaminated materials from patients with documented or suspected Creutzfeldt-Jakob disease. Ann Neurol


16. Brown P, Goldfarb LG, Gajdusek DC: The new biology of spongiform encephalopathy: Infectious amyloidoses with a genetic twist. Lancet 1991;337:1019-1022

17. Brown P: The phenotypic expression of different mutations in transmissible human spongiform encephalopathy. Rev Neurol (Paris) 1992;148:317-327

18. Collinge J, Brown J, Hardy J, et al: Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features. Brain 1992;115:687-71C

19. Hsiao K, Baker HF, Crow TJ, et al: Linkage of a prion protein missense variant to Gerstmann-Straussler syndrome. Nature 1989;338:342-345

20. Kitamoto T, Amano N, Terao Y, et al: A new inherited prion disease (PrP-P105L mutation) showing spastic paraparesis. Ann Neurol 1993;34:808-813

21. Tateishi J, Kitamoto T, Doh-ura K, et al: Immunochemical, molecular genetic, and transmission studies on a case of Gerstmann-Straussler- Scheinker syndrome. Neurology 1990;40:1578-1581

22. Kitamoto T, Iizuka R, Tateishi J: An amber mutation of prion protein in Gerstmann-Straussler-Scheinker syndrome with mutant PrP plaques. Biochem Biophys Res Commun 1993;192:525-53 .

23. Hsiao K, Dlouhy SR, Farlow MR, et al: Mutant prion proteins in Gerstmann-Straussler-Scheinker disease with neurofibrillary tangles. Nature Genet 1992;1:68-71

24. Gambetti P, Parchi P, Petersen RB, et al: Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Clinical pathological and molecular features. Brain Pathol 1995;5:43-51

25. Goldfarb LG, Petersen RB, Tabaton M, et al: Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Disease phenotype determined by a DNA polymorphism. Science 1992;258:806-808

26. Goldfarb LG, Brown P, Cervenkov L, Gajdusek DC: Molecular genetic studies of Creutzfeldt-Jakob disease. MolNeurobiol 1993;8:89-97

27. Pocchiari M, Salvatore M, Cutruzzol F, et al: A new point mutation of the prion protein gene in Creutzfeldt-Jakob disease. Ann Neurol 1993;34:802-807

28. Brown P, Cerven kov L, Goldfarb LG, et al: Molecular genetic testing of a fetus at risk of Gerstmann-Straussler-Scheinker syndrome. Lancet 1994;343:181-182

29. Duffy P, Wolf J, Collins G, et al: Possible person-to-person transmission of Creutzfeldt-Jakob disease. n Engl j Med 1974;290:692

30. Bernoulli C, Siegfried J, Baumgartner G, et al: Danger of accidental person-to-person transmission of Creutzfeldt-Jakob disease by surgery. Lancet 1977;I:478-479

31. Will RG, Matthews WB: Evidence for case-to-case transmission of Creutzfeldt-Jakob disease. j Neurol Neurosurg Psychiat 1982;45:235- 238

32. Brown P, Preece MA, Will RG: 'Friendly fire' in medicine: Hormones, homografts, and Creutzfeldt-Jakob disease. Lancet 1992;340:24-27

33. Brown P: Environmental causes of human spongiform encephalopathy. In Baker H, Ridley R (eds): Methods in Molecular Medicine. Totowa, NJ, Humana Press, 1996, pp 139-15 4.

34. Gibbs CJ Jr, Gajdusek DC, Latarjet R: Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie (unconventional viruses). Proc Natl Acad Sci (USA) 1978,75:6268- 6270

35. Brown P, Gibbs CJ Jr, Amyx HL, et al: Chemical disinfection of Creutzfeldt-Jakob disease virus. n Engl j Med 1982;306:1279-1282

36. Brown P, Rohwer RG, Gajdusek DC: Newer data on the inactivation of scrapie virus or Creutzfeldt-Jakob disease virus in brain tissue. j Infect Dis 1986;153:1145-1148

37. Taylor DM: Exposure to, and inactivation of, the unconventional agents that cause transmissible degenerative encephalopathies. In Baker h, Ridley r (eds): Methods in Molecular Medicine. Totowa, nj, Humana Press, 1996, pp 105-118


Was this article helpful?

0 0
Natural Cures For Insomnia

Natural Cures For Insomnia

How Would You Love To Finally Get A Decent Night's Sleep? Do you toss and turn all night long without getting much of a wink of sleep? Are you tired of counting sheep for hours without falling asleep? Wouldn't you love to be able to fall asleep simply, easily and naturally, without pills, potions or harmful medicine?

Get My Free Ebook

Post a comment