Supranuclear Control Of Eye Movements

As with other motor anatomical systems, conjugate gaze has lower motor nuclei and an upper motor neuron control system.

The upper motor neuron supranuclear control resides bilaterally in the cerebral cortex and cerebellum, and the control networks that produce conjugate gaze functions are the saccade, pursuit, and vestibulo-ocular systems, each with a specific anatomical arrangement in the cerebral hemispheres, brain stem, and cerebellum. All of the supranuclear systems are concerned with conjugate eye movements, and destructive lesions in these systems cause conjugate deviation in the direction of the unopposed antagonist muscles. Dysconjugate eye movements indicate a disorder at or below (peripheral to) the third, fourth, and sixth cranial nerve nuclei or in the pathways joining these nuclei.

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