Procedural habit learning and declarative memory

One example of a double dissociation involves the analysis of an unusual form of habit learning. Barbara Knowlton and her colleagues studied patients in the early stages of Parkinson's disease, associated with degeneration of neurons in a part of the brain stem (the substantia nigra) resulting in a major loss of input to the striatum, and a set of amnesic patients with hippocampal damage or damage elsewhere in that memory system. Subjects were trained in a probabilistic classification learning...

The striatal habit subsystem studies on human patients with striatal damage

In Chapter 8, it was shown that patients with striatal dysfunction associated with Parkinson's disease are impaired in probabilistic learning in a weather prediction task. This deficit is just one aspect of the deficit in habit learning in patients with striatal damage. Indeed, the deficit in probabilistic learning is among a number of findings in the clinical literature that raise questions about the scope of learning and memory impairments following striatal damage more specifically, about...