Natural Solution for Dry Scalp

No More Dry Scalp Dry Itchy Scalp & Dandruff Remedies

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Nomenclature of Malassezia yeasts

Malassezia yeasts were first identified in the late 1800s and in later studies different names have been used. Because of two main forms of the yeasts, an oval and a round form, their old names are Pityrosporum ovale and Pityrosporum orbiculare. In the current nomenclature the term Malassezia is favoured.

Atopy patch test with Malassezia

In a second study recombinant Malassezia allergens (Mal s 1, Mal s 5, and Mal s 6) were used in addition to M. furfur extract 21 67 of 132 patients with mild to severe AD were positive, while 13 of 14 patients with seborrhoeic dermatitis and all 33 healthy controls were negative.

Inflammatory Dermatologic Diseases Seborrhea

Seborrheic dermatitis is a chronic inflammatory disorder affecting areas of the head (scalp, face) and body where sebaceous glands are prominent. The inflammation is thought to be caused by Malassezia (Pityrosporum) species. All age groups may be affected, and seborrhea can be chronic or intermittent. On the scalp, seborrhea can range from mild dandruff to thick, adherent plaques. Seborrhea on the face and body appears as greasy scales in skin folds and along hair margins, with a symmetric distribution bilaterally. On the face, two common locations are around the eyebrows and around the beard and mustache in men (Fig. 33-16 and 33-17)

Notion Of Bucco-dental Superinfections

On the surmise that infection with Pityrosporum ovale is a major contributing factor to dandruff and that anti-Pityrosporum drugs such as nystatin were proven effective treatments, the use of 5 Melaleuca alternifolia essential oil was investigated. In this randomized, single-blind, parallel-group study tea tree oil shampoo or placebo shampoo was used daily for 4 weeks by 126 patients with mild to moderate dandruff. In the treatment group, the dandruff severity score showed an improvement of 41 , as compared to 11 in the placebo group. The area involvement and total severity scores also demonstrated a statistically significant improvement, as did itchiness and greasiness. Scaliness was not greatly affected. The condition resolved for one patient in each group and so ongoing application of tea tree oil shampoo was recommended for dandruff control (Satchell et al., 2002a).

Hypothesis on the Role of Complement Activation in type I Allergy Reactions

Neutrophils Fcr C3b

Complement fixation and precipitin reactions with the serum of broncial asthmatics who are sensitive to the proteins of wheat, horse dandruff, cat hair, and bacteria, using these proteins as antigens, and the cutaneous reaction as an index of sensitization. J Med Res 1917 36 243-246

Specific IgE antibodies to Malassezia

Dermatitis and Malassezia-furfur-specific IgE In the study from Bayrou specific IgE to Malassezia was found in all 106 serum samples of patients with HNAD, in 7 of the 25 patients with AD in other localisations, in 1 of 16 patients with seborrhoeic dermatitis and in none of the patients with contact dermatitis. A strong correlation was found between the severity of HNAD and specific IgE levels. Specific IgE antibodies to Malassezia were a very good and specific marker of HNAD in this study.4 Table 7.2 Skin prick tests to Malassezia in different populations. (Modified from Bayrou O, Pecquet C, Flahault A et al. Head and neck atopic dermatitis and Malassezia-furfur-specific IgE antibodies. Dermatology 2005 211 107-13.) Table 7.2 Skin prick tests to Malassezia in different populations. (Modified from Bayrou O, Pecquet C, Flahault A et al. Head and neck atopic dermatitis and Malassezia-furfur-specific IgE antibodies. Dermatology 2005 211 107-13.) Seborrhoeic dermatitis Seborrhoeic...

Skin colonization with Malassezia

The colonization of the skin with Malassezia was analysed in 112 individuals suffering from seborrhoeic dermatitis (20 of 39 were HIV-positive patients), pityriasis versicolor (18 patients), AD (18 patients), and 37 control patients without dermatological lesions. M. globosa was the most common species, isolated from 37.5 of the investigated individuals, followed by M. sympodi-alis in 31.3 , and M. furfur in 31.3 . In patients with pityriasis versicolor and in HIV-positive patients M. globosa was predominant in 67 and 85 of the cases. In non-HIV patients with AD or seborrhoeic dermatitis, M. furfur and M. restricta were isolated in 72 and 26 of the cases, respectively. It has been concluded that Malassezia species were present on the skin of patients with and without dermatological diseases. Malassezia globosa especially was found in a high frequency on the skin of patients with dermatological disorders suggesting a higher pathogenicity of this species.8

Pediculosis Clinical Summary

Pediculosis can be caused by either the body louse or the crab louse. Body lice are not sexually transmitted and tend to cluster around the waist, shoulders, axillae, neck, and head. They are extremely itchy patients may present with excoriations and intense pruritus. The lice are very small and may not be easily seen. The larval form of the louse, the nit, may be mistaken for dandruff in the hair. Unlike dandruff, however, the nits are extremely adherent to the hair shaft and cannot be brushed out of the hair. The adult lice and their eggs are often found in the seams of clothing.

Autonomic and Other Problems

Drooling may be accompanied by speech problems and dysphagia. Anticholinergics, botulinum toxin injections, and sublingual atropine can decrease drooling. Speech therapists perform swallowing studies to assess the risk of aspiration, and nutritionists optimize diet. Patients at high risk of aspiration or poor nutrition may require placement of a percutaneous endoscopic gastrostomy tube. Nausea improves if patients take their PD medications with meals or pharmacologic therapy (domperidone in Canada or trimethobenzamide). Sexual dysfunction or urinary problems may require a urolo-gic evaluation. Adjustment of PD therapy to increase on time, removal of drugs that decrease sexual response, and pharmacologic therapy (sildenafil or yohimbine) may help treat sexual dysfunction. Patients with urinary frequency may find a bedside urinal along with a decrease in evening fluids helpful. Improvement in PD symptom control can improve urinary frequency, but worsening symptoms may require...


Blepharitis is a chronic lid inflammation that involves abnormalities of the glands surrounding the eyelashes. The two most common types are chronic staphylococcal infections of the lid and seborrheic blepharitis (Fig. 41-6). Staphylococcal blepharitis is the most common inflammation of the external eye. It is frequently asymptomatic initially, but as the disease progresses, the patient complains of foreign body sensation, matting of the lashes, and burning. Lid crusting, discharge, redness, and loss of lashes are observed. Seborrheic blepharitis is associated with seborrhea of the scalp, lashes, eyebrows, and ears, characterized by greasy, dandruff-like scales on the lashes. Blepharitis is not associated with skin ulcerations.

Tinea Versicolor

Tinea versicolor presents with hypopigmented, pink brown macules and patches on the trunk with fine scale. Versicolor means varied colors, and this tinea tends to be white, pink, and brown (Fig. 33-51). Tinea versicolor is found on the back, chest, abdomen, and upper arms, often in a capelike distribution. Tinea versicolor is caused by Malassezia furfur (Pityrosporum), a lipophilic yeast that can be normal human cutaneous flora. Tinea versicolor is also called pityriasis versicolor after the causative organism. Pityrosporum is also associated with seborrhea, and thus antidandruff shampoos are effective in treating this tinea. Pityrosporum spp. thrive on sebum and moisture and tend to grow on the skin in areas where sebaceous follicles secrete sebum. Topical and oral treatments are effective, but tinea versicolor tends to recur, especially during the warmer months. The diagnosis can usually be made with the clinical examination, and if there is any doubt, a KOH prep can be examined for...


Stratum corneum - flat, cornified cells, overlapping each other as dry scales. If these scales remain intact, this top layer prevents the entry of harmful materials. Keratinization is completed here and gives the modified epidermal structures, e.g. hooves, beaks and hair their strength. Dead cells from this layer are continuously sloughed off as dandruff or scurf and replaced by new cells growing up from the base layer.

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