Chiral drugs have been in use in medicine throughout history. However, it is only in recent times that the importance of chirality in drug design and development has come to light. The tragic case of thalidomide highlighted the importance of testing the individual enantiomers of chiral drugs. This has spurred on the development of a range of methods for obtaining individual enantiomers of chiral drugs and for assessing their purity. There is no doubt that the proportion of drugs marketed as individual enantiomers will continue to rise as technological advances emerge to produce single enantiomers in bulk quantities.
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