Further Readings

Panic Away

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Baroni, M., Costantino, G., Cruciani, G., Riganelli, D., Valigi, R., and Clementi, S. 1993. Generating optimal linear PLS estimations (GOLPE): An advanced chemometric tool for handling 3D-QSAR problems. Quant. Struct. Act. Relat. 12:9-20. Dekermendjian, K., Kahnberg, P., Witt, M.-R., Sterner, O., Nielsen, M., and Liljefors, T. 1999. Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABAa receptor complex. J. Med. Chem. 42:4343-4350. Goodford, P. J. 1985. A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. J. Med. Chem. 28:849-857. Guner, O.F. (ed.) 2000. Pharmacophore Perception, Development and Use in Drug Design. International University Line, La Jolla.

Kahnberg, P., Lager, E., Rosenberg, C., Schougaard, J., Camet, L., Sterner, O., Nielsen, E. 0., Nielsen, M., and Liljefors, T. 2002. Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABAA receptor. J. Med. Chem. 45:4188-4201. Kahnberg, P., Howard, M. H., Liljefors, T., Nielsen, M., Nielsen, E. 0., Sterner, O., and Pettersson, I. 2004. The use of a pharmacophore model for identification of novel ligands for the benzodiazepine site of the GABAA receptor. J. Mol. Graph. Model. 23:253-261. Wold, S., Johansson, E., and Cocchi, M. 1993. PLS—Partial least squares projections to latent structures. In 3D QSAR in Drug Design: Theory, Methods, and Applications, Kubinyi, H. (ed.), ESCOM Science Publishers B.V., Leiden, the Netherlands, pp. 583-618. Zhang, W., Koehler, K. F., Zhang, P., and Cook, J. M. 1995. Development of a comprehensive pharmacophore model for the benzodiazepine receptor. Drug Des. Dev. 12:193-248.

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Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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