Catecholamine Effects

The influence of catecholamines on insulin secretion was initially thought to be inhibitory because norepinephrine and epinephrine were demonstrated to reduce the insulin secretory response to glucose.70'80'81 However, the influences of the catecholamines are dependent on the degree of expression of various adrenergic receptors. Thus, activation of postsynaptic a-adrenergic receptors, mainly of the 0C2 subtype on the islet B cells, inhibits insulin secretion,82 whereas activation of the ^-adrenergic receptors, mainly of the p2 subtype, stimulates insulin secretion.83 On the other hand, with regard to glucagon secretion, catecholamines seem to be stimulatory through the activation of both a- and ^-adrenergic receptors.84'85

Diabetes Sustenance

Diabetes Sustenance

Get All The Support And Guidance You Need To Be A Success At Dealing With Diabetes The Healthy Way. This Book Is One Of The Most Valuable Resources In The World When It Comes To Learning How Nutritional Supplements Can Control Sugar Levels.

Get My Free Ebook

Post a comment