Summary

These syndromes as well as others waiting to be described have endocrine features that require treatment. Earlier recognition of the syndromes and better surveillance for the different components of each syndrome should allow more effective treatment algorithms. Surgeons should be aware of these syndromes with endocrine involvement to better treat each individual patient and also to participate in family screening. Treating the preclinical stages of disease should allow the best possible outcome. Endocrine surgeons must remain involved if they are to keep intact their role as physician-teacher-researcher.

The findings from the human genome project are providing much useful information regarding genotype-phenotype relationships. These findings should lead to earlier diagnosis and more appropriate and effective therapies.

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