Patients with persistent or recurrent PHPT may present a challenge, even for the experienced parathyroid surgeon. Surgeons must reconfirm the diagnosis, consider the risks and benefits of reoperation, and review the operative note(s), pathology report(s), and results of the localization tests. The success rate of reoperation is quite good, especially in a patient whose tumor is identified by the preoperative localization tests, but the complication rate is appreciably higher than during initial parathyroid operations.


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