What damage can BPHcause

Enlargement of the prostate, BPH, increases the resistance to the flow of urine out of the bladder. Thus the bladder needs to work harder to push urine beyond the resistance. In order to accomplish this, the bladder pressures must increase. As a result of this need for increased force there is hypertrophy of the bladder muscle. The increased work that the bladder muscle needs to do to empty the bladder may lead to the development of overactive bladder (Questions 41 and 42). This increased pressure that the bladder needs to generate can be transmitted backwards from the bladder to the kidneys, and in some individuals it may impair the drainage of the kidneys, causing swelling of the kidneys/ hydronephrosis and a decrease in kidney function. If the bladder cannot create enough pressure and/or cannot maintain the elevated pressure, then the bladder may not empty completely. This residual urine may put some men at risk for bladder stones, bladder infections (UTI), and if the residual is significant, urinary leakage. Over the course of time, in some males, the bladder decom-pensates and acute urinary retention may occur, in which the male is unable to urinate. In some men, this is reversible with relief of the obstruction, in others, the bladder never recovers.

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