What is the success rate for PDE5 inhibitors

Overall, the PDE-5 inhibitors have a similar success rate. Success rates range from 48 to 81% with the various therapies, depending on the etiology of the ED. Individuals who have failed to respond to one of these medications may, however, respond to a different PDE-5 inhibitor. In one study, vardenafil was shown to be helpful in patients who had previously failed to respond to sildenafil therapy. However, studies have also demonstrated that patients who have failed an initial trial of sildenafil, when educated regarding proper use and rechallenged with sildenafil, have an increased likelihood of responding. Similarly, if you experience bothersome side effects with one medication, let your doctor know and your doctor may recommend trying a different PDE-5 inhibitor.

In men who have External-Beam Radiation Therapy-related erectile dysfunction, response rates range from 48 to 90%.

The response to PDE-5 inhibitors post-radical prostatectomy vary with several factors including patient's erectile status prior to the surgery and nerve-sparing status. The success rates of sildenafil for men who have undergone a bilateral nerve-sparing radical prostatectomy are approximately 70%; for those who have undergone a unilateral nerve-sparing radical prostatectomy, they are approximately 50%; and for those who have undergone a non-nerve-sparing radical prostatectomy, the success rates are approximately 15%.

PDE-5 inhibitors have been shown to be quite effective in reversing antidepressant-induced sexual dysfunction and antipsychotic-induced sexual dysfunction.

Dealing With Erectile Dysfunction

Dealing With Erectile Dysfunction

Whether you call it erectile dysfunction, ED, impotence, or any number of slang terms, erection problems are something many men have to face during the course of their lifetimes.

Get My Free Ebook


Post a comment