Info

Treatment

Cineole inhalation,

8 days Cineole 3 X 200 mg daily, 3 days

Cineole 3 X 200 mg daily, 12 weeks

Vaporub 3 min

Gelomyrtol 4 X 300 mg daily, 14 days

Cineole inhalation,

8 days Cineole 3 X 200 mg daily, 7 days Gelomyrtol 3 X 300 mg daily, 6 months

Gelomyrtol 4 X 0.3 g daily, 7 days Gelomyrtol 1 X 0.3 g daily, 14 days Cineole 4 X 200 mg,

4 days Cineole 3 X 200 mg daily, 8 weeks

Cineole 1 X 200 mg daily, 4 days

Cineole 3 X 200 mg daily, 7 days

Eucalyptus oil (9% of a mixture)

Gelomyrtol 300 mg,

6 days Cineole 3 X 200 mg daily, 7 days

Outcome

Asthma

Objective rise in expiratory peak flow found. Subjective experiences of illness significantly improved LTB4 and PGE2 production by monocytes was significantly inhibited. Lung functions were significantly improved Twelve of 16 patients in cineole group remained stable despite a 36% reduction in oral steroid dosage Acute bronchitis Decreased breathing frequency, suggesting "easier breathing"

Coughing, sputum consistency, well-being, bronchial hyperreactivity, and associated symptoms all improved similarly by Gelomyrtol, Ambroxol, and Cefuroxime

Chronic bronchitis Objective rise in expiratory peak flow found. Subjective experiences of illness significantly improved All lung function parameters significantly improved

Reduced acute exacerbations, reduced requirement for antibiotics, reduced treatment times when antibiotics taken. Well-being significantly improved COPD

Improved mucociliary clearance

All parameters relating to coughing improved.

Sputum volume increased Significant improvement of mucociliary clearance

Significant improvement in airway resistance (21%), positive effects on sputum output and dyspnea

Significant improvements in lung functions of FVC and FEV1 (Ambroxol and cineole equieffective), significant increase in ciliary beat frequency All lung function parameters, peak flow and dyspnea improved from day 1 onward

Common cold

Reversed lung function abnormalities in small and large airways

Sinusitis

Effective treatment instead of antibiotics

Effective reduction of symptoms without the need for antibiotics

Reference

Grimm (1987)

Juergens et al. (1998c)

Juergens et al. (2003)

Berger et al.

Grimm (1987) Mahlo (1990)

Meister et al. (1999)

Dorow et al.

Habich and Repges (1994) Kaspar et al. (1994)

Wittmann et al. (1998)

Cohen and Dressler (1982)

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