8 days Cineole 3 X 200 mg daily, 3 days
Cineole 3 X 200 mg daily, 12 weeks
Vaporub 3 min
Gelomyrtol 4 X 300 mg daily, 14 days
8 days Cineole 3 X 200 mg daily, 7 days Gelomyrtol 3 X 300 mg daily, 6 months
Gelomyrtol 4 X 0.3 g daily, 7 days Gelomyrtol 1 X 0.3 g daily, 14 days Cineole 4 X 200 mg,
4 days Cineole 3 X 200 mg daily, 8 weeks
Cineole 1 X 200 mg daily, 4 days
Cineole 3 X 200 mg daily, 7 days
Eucalyptus oil (9% of a mixture)
Gelomyrtol 300 mg,
6 days Cineole 3 X 200 mg daily, 7 days
Objective rise in expiratory peak flow found. Subjective experiences of illness significantly improved LTB4 and PGE2 production by monocytes was significantly inhibited. Lung functions were significantly improved Twelve of 16 patients in cineole group remained stable despite a 36% reduction in oral steroid dosage Acute bronchitis Decreased breathing frequency, suggesting "easier breathing"
Coughing, sputum consistency, well-being, bronchial hyperreactivity, and associated symptoms all improved similarly by Gelomyrtol, Ambroxol, and Cefuroxime
Chronic bronchitis Objective rise in expiratory peak flow found. Subjective experiences of illness significantly improved All lung function parameters significantly improved
Reduced acute exacerbations, reduced requirement for antibiotics, reduced treatment times when antibiotics taken. Well-being significantly improved COPD
Improved mucociliary clearance
All parameters relating to coughing improved.
Sputum volume increased Significant improvement of mucociliary clearance
Significant improvement in airway resistance (21%), positive effects on sputum output and dyspnea
Significant improvements in lung functions of FVC and FEV1 (Ambroxol and cineole equieffective), significant increase in ciliary beat frequency All lung function parameters, peak flow and dyspnea improved from day 1 onward
Reversed lung function abnormalities in small and large airways
Effective treatment instead of antibiotics
Effective reduction of symptoms without the need for antibiotics
Juergens et al. (1998c)
Juergens et al. (2003)
Berger et al.
Grimm (1987) Mahlo (1990)
Meister et al. (1999)
Dorow et al.
Habich and Repges (1994) Kaspar et al. (1994)
Wittmann et al. (1998)
Cohen and Dressler (1982)
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