Accuracy of Screening Tests

Standard testing for HIV infection with the repeatedly reactive enzyme immunoassay, followed by confirmatory Western blot or immunofluorescent assay, has a sensitivity and specificity greater than 99%. False-positive test results are rare, even in low-risk settings. Compared with standard HIV testing, the reported sensitivities of rapid tests on blood specimens range from 96% to 100%, with specificities greater than 99.9%. Reported sensitivities and specificities of oral fluid HIV tests are also high (>99%) (Chou et al., 2005).

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