Amylin Pramlintide

Amylin is a peptide secreted normally from the pancreas in equimolar amounts with insulin after a meal. It is thought to regulate gastric motility and the release of carbohydrates into the absorptive surfaces of the gut. Pramlintide is an amylin mimetic injected subcutaneously with meals, initially approved to be given with insulin in type 1 diabetic patients. The effect is usually modest to negligible, but anecdotal experience indicates that an occasional brittle diabetic patient may experience dramatic improvement. Pramlintide is now also used in type 2 patients with or without insulin because of its mild effect in limiting food intake and causing weight loss. Pramlintide is therefore used as a tertiary agent when other, more widely used drugs are not fully efficacious.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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