Anemia Key Points

• Anemia is a reduced RBC mass, resulting in decreased oxygen-carrying capacity of the blood (>2 SD from mean for age, gender, and race).

• Patients with unrecognized anemia often present with symptoms of fatigue, loss of stamina, shortness of breath, and tachycardia (with exercise).

• Acute blood loss or anemia is almost always caused by hemorrhage or hemolysis.

• Loss of 30% of blood volume results in postural symptoms; loss of 40% blood volume produces signs of shock.

• Bone marrow responsiveness to anemia is best evaluated by reticulocyte index and marrow production index.

• Anemias can be best understood by classifying them into three types: hypoproliferative anemia, maturation disorders, and hemolytic-hemorrhagic anemia.

• Anemia of chronic disease is a hypoproliferative anemia now referred to as the anemia of inflammation (AI).

• Serum ferritin is normal or increased in AI and low in true iron deficiency

• Treatment of folate deficiency with alcoholic neuropathy without confirming vitamin B12 deficiency may result in a progressively worsening neuropathy.

• Values below lower limits of normal for age/gender indicate only 25% likelihood that the person is not anemic.

• If creatinine is greater than 2 mg/dL and no other cause for anemia can be found, the anemia probably results from renal inefficiency.

• Bilirubin gallstones occur in 40% to 60% of sickle cell disease patients.

• The absence of free haptoglobin is diagnostic of hemolytic anemia.

• Sickle cell disease is a form of hemolytic anemia; thrombosis is more common in children, whereas hemorrhage occurs more often in adults with sickle cell disease.

• Coombs test is the diagnostic choice for autoimmune hemolytic anemia.

Curing Eczema Naturally

Curing Eczema Naturally

Do You Suffer From the Itching, Redness and Scaling of Chronic Eczema? If so you are not ALONE! It strikes men and women young and old! It is not just

Get My Free Ebook


Post a comment