A GABA-B receptor agonist, baclofen has long been used as an antispasmodic. Only more recently has baclofen been investigated as a treatment for alcohol dependency. In a modest controlled trial of 1 month, baclofen was efficacious in achievement of total abstinent days compared with placebo (Addolorato et al., 2002). A follow-up study demonstrated efficacy in 84 patients with cirrhosis of the liver in maintaining abstinence (71% baclofen vs. 29% placebo) (Addolorato et al., 2007). There is potential for abuse of baclofen and withdrawal reactions, including delirium, which underscores the need for further research (Kanzler et al., 2009).

Beat The Battle With The Bottle

Beat The Battle With The Bottle

Alcoholism is something that can't be formed in easy terms. Alcoholism as a whole refers to the circumstance whereby there's an obsession in man to keep ingesting beverages with alcohol content which is injurious to health. The circumstance of alcoholism doesn't let the person addicted have any command over ingestion despite being cognizant of the damaging consequences ensuing from it.

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