Central Nervous System Infection and Inflammation

Key Points

• Bacterial meningitis is a neurologic emergency.

• Acute bacterial meningitis has a high morbidity and mortality.

• Antibiotic therapy should be started as soon as possible after meningitis is considered likely, usually by CSF analysis.

• Knowing the most prevalent organisms that cause bacterial meningitis in different age groups is important in guiding therapy.

• Gram stain of CSF is recommended for all patients with suspected bacterial meningitis.

• Adjunctive dexamethasone therapy for infants, children, and adults who have already received antibiotics is not recommended.

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