Classic

Infections: Abscesses, endocarditis, tuberculosis (TB), complicated urinary tract infection (UTI).

Geographic location: Leishmaniasis (Spain), melioidosis (Southeast Asia, Australia), Kikuchi-Fujimoto disease (form of necrotizing lymphadenitis, Japan). Connective tissue diseases: Juvenile rheumatoid arthritis (JRA, Still's disease), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), temporal arteritis, polymyalgia rheumatica (PMR). Neoplasms: malignant neoplasm, lymphoma, leukemia. Other: Familial Mediterranean fever in Ashkenazi Jews.

Infants and Children

Respiratory infections predominate if <12 years.

Kawasaki disease if <5 years.

JRA, (Still's disease) in the older child/young adult.

Elderly

Connective tissue diseases are more prominent. Travelers

Infections: Malaria, hepatitis, pneumonia/bronchitis, UTI/pyelonephri-tis, dysentery, dengue fever, enteric fever, TB, rickettsial infection, acute human immunodeficiency virus (HIV) infection, amebic liver abscess.

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