Cyanosis

One needs to differentiate central cyanosis, which is always pathologic, from peripheral cyanosis involving the hands and feet (acrocyanosis). Acrocyanosis is normal in the first few days of life. The infant with true generalized or central cyanosis should be given oxygen immediately and the cause of cyanosis should be investigated. The major causes of cyanosis are cardiac anomalies, respiratory problems, and sepsis. The approach to evaluation and management of cyanosis has been well described (Sasidharan, 2004).

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