Frontotemporal Lobar Degenerations

Frontotemporal dementia (FTD), formerly called Pick's disease, is the most common of three frontotemporal lobe degenerations (FTLDs). The other two are progressive aphasia and semantic dementia. FTD often presents with disordered behavior as a result of impairment in executive function, motivation, goal setting, and sequencing of plans. Labile mood and social disinhibition are common even before cognitive testing shows an abnormality. Neuroimag-ing often shows frontal or temporal lobe atrophy; formal psychometric testing is useful to confirm the diagnosis. There are no specific treatments (Liscic et al., 2007).

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