Hypersensitivity Pneumonitis

Exposure to organic materials such as fungi, plant proteins, animal danders, or other organic dust can cause a similar type of diffuse parenchymal lung disease known as hypersensitivity pneumonitis. Examples include farmers'

Welding exposures Polymers Hydrocarbons, n.o.s.

Solvents Isocyanates Pyrolysis products Indoor air pollutants Mineral and inorganic dust Cleaning materials Miscellaneous chemicals

10 % cases


Figure 18-9 Causes of work-related asthma, 1993-1999. (From National institute for Occupational Safety and Health. Distribution of agent categories most often associated with work-related asthma cases for all four SENSOR reporting States [California, Massachusetts, Michigan, New Jersey], 1993-1999. Worker Health Chartbook 2004. http://www2a.cdc.gov/niosh-Chartbook/imagedetail.asp?imgid=206.)

I I Contributing cause I I Underlying cause


1968 1972 1976 1980 1984 1988 1992 1996

Figure 18-10 Asbestos as a contributing or underlying cause of death in the United States, 1968-1999. (From National Institute for Occupational Safety and Health: Number of deaths of U.S. residents aged 15 or older with asbestosis recorded as an underlying or contributing cause on the death certificate, 1968-1999. Worker Health Chartbook, 2004. http:// www2a.cdc.gov/NIOSH-Chartbook/imagedetail.asp?imgid=2l7.)

lung, mushroom workers' lung, and bird fanciers' disease. Although fewer than 100 deaths per year in the United States are directly attributed to hypersensitivity pneumonitis, the number of cases and resulting short-term or long-term disability are potentially much higher.

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