Primary Sjogrens syndrome

A. Symptoms and objective signs of ocular dryness

1. Schirmer's test <8 mm wetting per 5 minutes, and

2. Positive rose bengal staining of cornea or conjunctiva to demonstrate keratoconjunctivitis sicca

B. Symptoms and objective signs of dry mouth

1. Decreased parotid flow rate using a Lashley cup or other method and

2. Abnormal findings from biopsy of minor salivary gland (focus score of >1 based on average of four evaluable lobules)

C. Serologic evidence of a systemic autoimmunity

1. Elevated rheumatoid factor >1:320 or

2. Elevated antinuclear antibody <1:320 or

3. Presence of anti-SS-A(Ro) or anti-SS-B(La) antibodies

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