Key Points

• The hypothalamic-pituitary axis orchestrates the hormonal secretions of the other endocrine glands.

• The pituitary is composed of the adenohypophysis (anterior lobe) and neurohypophysis (posterior lobe).

• The hormonal secretions of the anterior pituitary are regulated by hypothalamic releasing hormones and inhibitory molecules.

• The posterior pituitary lobe is where nerve endings, originating in the paraventricular and supraoptic nuclei, project as the supraopticohypophyseal tract.

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