Key Points

• The hallmark clinical features of Parkinson's disease include resting tremor, rigidity and bradykinesia of asymmetric onset.

• Symptoms such as hallucinations, gait abnormalities, paralysis of upward gaze, early dementia, early postural instability, early autonomic dysfunction, involuntary movements other than a tremor and a failure to respond to levodopa suggest a parkinsonism-plus syndrome and require further evaluation.

• Drug therapy for Parkinson's disease should be initiated when the symptoms are significant enough to cause functional impairment.

Parkinson's disease is the second most common progressive neurodegenerative disorder in the United States after Alzheimer's disease. Parkinson's affects about 1% of the population over age 60 and 4% to 5% of those older than 85. The disease is uncommon before age 40, and incidence is higher in men than women. A genetic predisposition to Parkinson's disease may be present; up to 15% of patients will have a first- or second-degree relative with Parkinson's

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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