Key Treatment

Spontaneous bacterial peritonitis is treated with third-generation cephalosporins (cefotaxime or ceftriaxone), with ampicillin-sul-bactam, fluoroquinolones, or carbapenems as alternative agents (Solomkin et al., 2010) (SOR: B).

Patients with diffuse peritonitis should undergo an emergency surgical procedure as soon as possible, even if ongoing measures to restore physiologic stability need to be continued during the procedure (Solomkin et al., 2010) (SOR: B).

Discussions of the following infections can be found online at

• Secondary bacterial peritonitis and intra-abdominal abscesses

• Cholecystitis

• Cholangitis

• Appendicitis

• Diverticulitis

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