Key Treatment

Patients with acute group A streptococcal pharyngitis should receive antibiotic therapy to help prevent the complication of acute rheumatic fever (Denny et al., 1950) (SOR: B). Patients with acute rheumatic fever should receive appropriate antibiotic therapy to eradicate the GAS infection, regardless of whether pharyngitis is present at diagnosis (SOR: C). Use of aspirin is the treatment of choice for the acute symptoms of acute rheumatic fever (SOR: C).

Prevention of recurrent acute rheumatic fever requires prophylactic treatment for GAS pharyngitis with antibiotics (Gerber et al., 2009) (SOR: A).

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