Key Treatment

NSAIDs are the mainstay of treatment for symptomatic reactive arthritis but do not alter or shorten its course (SOR: C). Intra-articular injections can be helpful and are not contraindicated in Reiter's syndrome (SOR: C).

When there is unsatisfactory response to NSAIDs or steroid injections, a trial of sulfasalazine is suggested for patients with reactive arthritis (SOR: C).

For patients with contraindications or intolerance to sulfasalazine, a trial of etanercept can be attempted (SOR: C).

NSAIDs are the first line of treatment for psoriatic arthritis (Cuellar et al., 1994) (SOR: B).

Methotrexate and sulfasalazine have proven efficacy in the treatment of psoriatic arthritis (Jones et al., 2000) (SOR: B); used as second-line agents if inadequate response to NSAIDs. Patients with axial disease or who have peripheral disease without improvement to DMARD treatments are candidates for anti-TNF medications, which have proven efficacy (Saad et al., 2008) (SOR: A).



Thank you for deciding to learn more about the disorder, Osteoarthritis. Inside these pages, you will learn what it is, who is most at risk for developing it, what causes it, and some treatment plans to help those that do have it feel better. While there is no definitive “cure” for Osteoarthritis, there are ways in which individuals can improve their quality of life and change the discomfort level to one that can be tolerated on a daily basis.

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