Key Treatment

NSAIDs are the mainstay of treatment for symptomatic reactive arthritis but do not alter or shorten its course (SOR: C). Intra-articular injections can be helpful and are not contraindicated in Reiter's syndrome (SOR: C).

When there is unsatisfactory response to NSAIDs or steroid injections, a trial of sulfasalazine is suggested for patients with reactive arthritis (SOR: C).

For patients with contraindications or intolerance to sulfasalazine, a trial of etanercept can be attempted (SOR: C).

NSAIDs are the first line of treatment for psoriatic arthritis (Cuellar et al., 1994) (SOR: B).

Methotrexate and sulfasalazine have proven efficacy in the treatment of psoriatic arthritis (Jones et al., 2000) (SOR: B); used as second-line agents if inadequate response to NSAIDs. Patients with axial disease or who have peripheral disease without improvement to DMARD treatments are candidates for anti-TNF medications, which have proven efficacy (Saad et al., 2008) (SOR: A).

Arthritis Relief Now

Arthritis Relief Now

When you hear the word arthritis, images of painful hands and joints comes into play. Few people fully understand arthritis and this guide is dedicated to anyone suffering with this chronic condition and wants relief now.

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