Key Treatment

Sunscreen twice daily for 7 months may protect against development of actinic dermatoses (de Berker et al., 2007) (SOR: A). Treating AKs with liquid nitrogen showed complete response of up to 83% for freeze times greater than 20 seconds (Thai et al., 2004) (SOR: A). Treat multiple AKs of the face, scalp, forearms, and hands topically with 5-FU, imiquimod, or diclofenac (de Berker et al., 2007) (SOR: A). Average complete clearance of AKs using 5-FU was 52% (±18%) and for imiquimod, 70% (±12%) (Gupta et al., 2006) (SOR: A).

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