Other Syndromes

Syndromes involving chromosomes (Down, Klinefelter's), fat and muscle metabolism (Prader-Willi, myotonic dystrophy), and autoimmune mechanisms (stiff man syndrome) can affect insulin secretion or sensitivity.

Inflammatory attack

Aging, 1° IR or 2° excess nutrient storage

Figure 34-1 How normal or genetically impaired beta cells can be affected by inflammation and overnutrition, resulting in absolute or relative loss of insulin secretory reserve and the activation of the common mechanism leading to diabetic crisis. 1°IR, Primary insulin resistance; 2°IR, secondary insulin resistance; DKA, diabetic ketoacidosis; FFA, free fatty acids; TRG, triglycerides.

Figure 34-1 How normal or genetically impaired beta cells can be affected by inflammation and overnutrition, resulting in absolute or relative loss of insulin secretory reserve and the activation of the common mechanism leading to diabetic crisis. 1°IR, Primary insulin resistance; 2°IR, secondary insulin resistance; DKA, diabetic ketoacidosis; FFA, free fatty acids; TRG, triglycerides.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

Get My Free Ebook


Post a comment