Peyronies Disease

Peyronie's disease is characterized by formation of fibrosis in the tunica albuginea, with resulting penile deformity and pain. Symptoms include painful erection, physical penile deformity (often curvature), palpable penile plaque (fibrosis), and erectile dysfunction. Pain is typically transient, and most cases do not result in a deformity so severe that it impairs intercourse. Sexual history, counseling, and partner involvement are important, because Peyronie's disease can be disruptive to a relationship. Most patients do not require any treatment beyond reassurance and counseling. Nonsurgical treatments are available (e.g., colchicine, intralesional verapamil), but supporting evidence is limited, and urologic consultation should be considered before exploring treatment. Steroid injection is best avoided. Surgery is an option in severe cases (Lewis and Munarriz, 2007).

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