Some patients may require minimal to mild conscious sedation during a procedure in the outpatient clinic setting. Use of a low-dose benzodiazepine, such as 1 to 2 mg of loraz-epam or 0.5 to 1 mg of alprazolam, may be appropriate for light conscious sedation. Sedation may also be accomplished with a dose of an oral opioid, such as hydrocodone or oxycodone. These patients should not operate a car or heavy machinery, and another person should provide their transportation. Use of an opioid in combination with a ben-zodiazepine may cause significant respiratory depression.

This mixture is usually considered moderate to heavy sedation and requires additional constant monitoring of cardiac and oxygenation status, which may not be available in some ambulatory clinical practices.

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