Squamous Cell Carcinoma

Cutaneous squamous cell carcinoma is the second most common form of skin cancer, also arising primarily on sun-exposed skin of middle-aged and older adults. Most SCCs arise from sun-induced precancerous lesions (actinic keratoses). As in BD, there is a higher risk of SCC in patients with radiation dermatitis (x-ray damage), leukoplakia or erythro-plakia (in oral or genital mucosa), burn scars, and chronic skin ulcers. It is important to note that organ transplant recipients have a 40 to 250 times greater risk of developing SCC, purportedly from interaction of HPV and immuno-suppression.

Lesions are typically pink to flesh-colored papules or nodules, often with crusting or ulceration (Fig. 33-84). They may also be keratotic or may develop a cutaneous horn. The most common locations include the face, scalp, lips, ears, neck, dorsal arms and hands, and genitalia (Fig. 33-85). Although many SCCs are asymptomatic, symptoms such as bleeding, pain, and tenderness, may be noted. SCC has an overall metastasis rate of 2% to 3%, but it is highly variable based on location, size, depth, invasion, and immunosuppression;

Figure 33-84 Squamous cell carcinoma under ear. © Richard P. Usatine.)

Figure 33-85 Squamous cell carcinoma on lip. © Richard P. Usatine.)

underwent MMS, recurrence after MMS was diagnosed in 15 of the 381 patients (3.9%) who completed the 5-year follow-up: 2.6% in patients with primary SCC, and 5.9% in patients with previously recurrent SCC (Leibovitch et al., 2005).

Was this article helpful?

0 0
How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

Get My Free Ebook

Post a comment