Some sarcoidosis patients may require no treatment, or only intermittent nonsteroidal anti-inflammatory drugs (NSAIDs) for joint and constitutional symptoms. Topical corticosteroids may be effective for anterior uveitis and some skin lesions. Inhaled corticosteroids and bronchodilators are often used when cough is a prominent symptom in patients with pulmonary involvement, but response has been equivocal. Systemic therapy is needed for the majority of patients. Systemic corticosteroids are first-line therapy and, for patients with pulmonary involvement, improve symptoms, pulmonary function, and chest x-ray signs of disease.

Second-line therapies include cytotoxic agents and other immunomodulating agents (Baughman et al., 2008). Meth-otrexate and hydroxychloroquine can be used as steroid-sparing agents. In patients with cardiac or neural sarcoidosis, treatment regimens that include cytotoxic therapy (e.g., cyclo-phosphamide) are needed. Other treatment strategies include agents that inhibit tumor necrosis factor alpha (infliximab, adalimumab, etanercept) (Nunes et al., 2005). Comorbid illnesses and multiorgan involvement are common in sarcoid-osis (Cox et al., 2004; Westney et al., 2007), so health-related quality-of-life instruments should be used to monitor global response to therapy (DeVries and Drent, 2007), and multidis-ciplinary team-based care is recommended.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

Get My Free Ebook

Post a comment