In Vivo and In Vitro Antioxidant Treatments

Oral antioxidant supplements may be used to counteract OS and treat male infertility. Studies have shown that antioxidants correlate with improvement in sperm parameters; however, in excess, these oral antioxidant supplements may have detrimental effects [83]. As an example, improvement in sperm motility and lower levels of ROS were attributed to vitamin E and selenium oral supplementation [84]. Other antioxidant supplementations that have been proven to be effective in reducing ROS levels include glutathione, l-carnitine, vitamin A, and ^-acetyl cysteine [39, 50].

Antioxidant treatments can be also added to culture media in vitro during sperm preparation techniques in order to improve in vitro sperm fertilization ability. Vitamin C supplementation alone and in conjunction with vitamin E has been shown to be effective both orally and in culture media [85, 86]. Media supplementation with vitamin C and urate can lead to protection of spermatozoa from DNA damage [87].

Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

Get My Free Ebook


Post a comment