Oxidative Stress and Gamete Cryopreservation

Cryopreservation enhances production of ROS that induce membrane LPO, DNA damage, and apoptosis in frozen spermatozoa1 [206] . Removing the seminal plasma leaves spermatozoa unprotected by antioxidants which will affect cryopre-served spermatozoa negatively. The addition of antioxidants to the thawing media improves spermatozoa function and in vitro fertilizing capabilities [215]. DNA damage was reported in cryopreserved oocytes due to oxidative stress [216]. Using the antioxidant vitamin C in the culture media reduces the stromal tissue apoptosis and damage [217].

Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

Get My Free Ebook


Post a comment