Seminal Antioxidants

Depending on the solubility in water or in lipids, antioxidants can be classified into two main divisions: hydrophilic which are water-soluble or hydrophobic which are lipid-soluble. In general, water-soluble antioxidants react with oxidants in the cell cytosol and the blood plasma, while lipid-soluble antioxidants protect cell membranes from lipid peroxidation. These compounds can be formed in the body or obtained from the diet [26].

The different types of antioxidants are present at various concentrations in body fluids and tissues, with some such as glutathione or ubiquinone mostly present within cells, while others such as uric acid being more evenly distributed. Some compounds contribute to antioxidant defense by chelating transition metals and preventing them from catalyzing the production of free radicals in the cell. Particularly important is the ability to sequester iron, which is the function of iron-binding proteins such as transferrin and ferritin. Selenium and zinc are commonly referred to as antioxidant nutrients; however, these chemical elements have no antioxidant action themselves and are instead required for the activity of some antioxidant enzymes [27],

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