Summary Statements

• In humans, epidemiological studies indicate that there is a reduction in germ cell quality past the age of 35 years.

• Aging is associated with increased oxidative stress and decreased antioxidants.

• Rodent studies show that aging male germ cells display an increase in ROS and reduction in the antioxidant enzymes normally present that neutralize ROS and protect the cellular structures against ROS-induced damage.

• Studies using animal models demonstrate that advanced paternal age is associated with adverse progeny outcome.

• DNA damage increases and DNA repair decreases with age.

Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

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