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Anon. 1811. Disease in Ohio ascribed to some deleterious quality in milk of cows. Medical Repository [N.Y.] 3: 92-4.

Couch, James F. 1928. Milk sickness, result of richweed poisoning. Journal of the American Medical Association 91: 234-6. Furbee, Louanna, and William D. Snively, Jr. 1968. Milk sickness, 1811-1966: A bibliography. Journal of the History of Medicine 23: 276-85. Hartmann, Alexis F., Sr., et al. 1963. Tremetol poisoning -not yet extinct. Journal of the American Medical Association 185: 706-9. Jordan, Edwin O., and Norman MacL. Harris. 1909. Milk sickness. Journal of Infectious Diseases 6: 401-91. Jordan, Philip D. 1944. Milk sickness in the western country together with an account of the death of Lincoln's mother. Ohio State Medical Journal 40: 848-51.

McKeever, George E. 1976. Milk sickness: A disease of the Middle West. Michigan Medicine 72: 775-80.

Moseley, Edwin L. 1941. Milk sickness caused by white snakeroot. Ann Arbor, Mich.

Snively, William D., Jr. 1967. Mystery of the milksick. Minnesota Medicine 50: 469-76.

Snively, William D., Jr., and Louanna Furbee. 1956. Discovery of the cause of milk sickness. Journal of the American Medical Association 196: 1055-60.

Multiple sclerosis is a disease of the central nervous system characterized clinically by recurring episodes of neurological disturbance which, especially early in the course of the disease, tend to remit spontaneously, although as time goes by there is often a gradual accumulation of disability. The course of the disease is quite variable, at one extreme lasting for 50 years without the development of significant disability, and at the other terminating fatally in a matter of months. Overall, about one quarter of patients remain able to work for up to 15 years after the first recognized clinical manifestation, and the mean duration of life is approximately 25 years from that time. Nevertheless, because the disease commonly affects young adults and produces disability in the prime of life, the economic burden is heavy, in the United States averaging $15,000 per annum per family with a member afflicted (Inman 1983 data, cited in McDonald and Silberberg, eds. 1986, 180).

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