Distribution and Incidence

The disease appears to have its greatest prevalence in Europe and in regions inhabited by European emigrants such as Australia, New Zealand, and areas of South America. For no apparent reason, the disease is distinctly uncommon in African blacks, Orientals, and inhabitants of India and Scandinavia. Where studied, the incidence ranges between 3.5 and 4.5 percent of the population in high prevalence regions of the world, with a high of 8.3 percent in a part of Lancashire, England, to a low of 0.4 percent in Sweden. In a U.S. survey of Paget's disease based on pelvic X-rays, the incidence was 3.9 percent in Caucasians residing in Brooklyn and 0.9 percent in Caucasians residing in Atlanta. Similarly, 1,000 pelvic X-rays revealed no Paget's disease in Lexington, Kentucky, and 1.1 percent pelvic Paget's disease in Providence, Rhode Island.

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