History and Geography

Early in this century, pathologists noted the enlarged cells with inclusion bodies in organs of children dying of presumed congenital syphilis. The inclusions were thought to be amebae. In 1921 E. W. Goodpasture and F. B. Talbot noted their similarity to changes found in varicella and guessed they represented viral infection and described the cellular enlargement as "cytomegaly." The virus was isolated in 1956 by investigators working independently in St. Louis, Boston, and Bethesda. Epidemiological studies became feasible with the recognition of antibodies to the virus in 1968. A rapid expansion of knowledge concerning epidemiology, incidence, and clinical manifestations continues from the late 1960s.

R. H. Kampmeier

Your Heart and Nutrition

Your Heart and Nutrition

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