Treatment modalities are being explored. Ribavirin shows promise of benefits if administered early enough in the course of disease (McCormick et al. 1987a,b). An early hope in treatment, administration of plasma from recovered cases, has not been very successful. If given early enough, before a positive laboratory diagnosis is possible, it may have some value. Given later, there have been occasional dramatic recoveries, as in the case of Yale's Jordi Casals. But there have also been many failures. Renal shutdown has been a fatal feature of such treatment in some instances. All work with Lassa virus must be conducted under conditions of highest security (MMWR 1983), which slows down laboratory work. Several human deaths have occurred among laboratory workers, nonetheless.

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