Glues Bioadhesives and Hemostatic Agents

Details of various biological hemostatic and tissue agents are detailed elsewhere in the text. Closure of laparoscopic port-site incisions with skin adhesives such as octyl-cyanoacrylate has been found to be as effective as subcuticular suturing with the advantage of requiring less operative time (9). Although there are other adhesives such as N-butyl-2-cyanoacrylate, only octylcyanoacrylate has the approval of the Food and Drug Administration. octylcyanoacrylate has to be applied to dry, well-approximated incisions and the product must not be allowed to come in contact with subcutaneous tissues as a vigorous foreign body reaction resembling an infection often ensues.

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